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Antioxidant and cytoprotective activities of the selected lycopene nanoparticle formulation. (A) DPPH radical-scavenging activities of free lycopene and NL-5. (B) Viability of H 2 O 2 -stressed HepG2 cells following pretreatment with free lycopene and NL-5. Data are presented as mean ± SD ( n = 3).

Journal: RSC Advances

Article Title: Formulation-dependent colloidal properties of redispersible lycopene nanoparticles: storage stability and enhanced in vitro bioactivity

doi: 10.1039/d6ra08147a

Figure Lengend Snippet: Antioxidant and cytoprotective activities of the selected lycopene nanoparticle formulation. (A) DPPH radical-scavenging activities of free lycopene and NL-5. (B) Viability of H 2 O 2 -stressed HepG2 cells following pretreatment with free lycopene and NL-5. Data are presented as mean ± SD ( n = 3).

Article Snippet: HepG2 cells (ATCC HB-8065) were cultured in high-glucose DMEM supplemented with 10% FBS, 100 U per mL penicillin, and 100 μg per mL streptomycin at 37 °C in a humidified 5% CO 2 atmosphere.

Techniques: Formulation

Effects of free lycopene and NL-5 on intracellular lipid accumulation in OA-treated HepG2 cells. (A) Inhibition of intracellular lipid accumulation by free lycopene and NL-5. (B) Cell viability following treatment with free lycopene and NL-5. Lovastatin (10 µM) was used as the positive control. (C) Representative Oil Red O-stained micrographs of untreated control, OA control, lovastatin-treated, free-lycopene-treated, and NL-5-treated cells. Data are presented as mean ± SD ( n = 3).

Journal: RSC Advances

Article Title: Formulation-dependent colloidal properties of redispersible lycopene nanoparticles: storage stability and enhanced in vitro bioactivity

doi: 10.1039/d6ra08147a

Figure Lengend Snippet: Effects of free lycopene and NL-5 on intracellular lipid accumulation in OA-treated HepG2 cells. (A) Inhibition of intracellular lipid accumulation by free lycopene and NL-5. (B) Cell viability following treatment with free lycopene and NL-5. Lovastatin (10 µM) was used as the positive control. (C) Representative Oil Red O-stained micrographs of untreated control, OA control, lovastatin-treated, free-lycopene-treated, and NL-5-treated cells. Data are presented as mean ± SD ( n = 3).

Article Snippet: HepG2 cells (ATCC HB-8065) were cultured in high-glucose DMEM supplemented with 10% FBS, 100 U per mL penicillin, and 100 μg per mL streptomycin at 37 °C in a humidified 5% CO 2 atmosphere.

Techniques: Inhibition, Positive Control, Staining, Control